According to Bethesda, you'll need at least an Intel Core i5-3570 or AMD Ryzen 3 1300X CPU, 8GB of RAM, and either an Nvidia GTX 780 3GB or AMD R9 280 3GB graphics card to play the game. It also needs a 64-bit Windows 7, Windows 8.1 or Windows 10 OS, as well as 50GB of storage space.
In case you want to push those graphics details higher and use a higher resolution, you'll need an Intel Core i7-4770 or AMD Ryzen 5 1600X CPU, 8GB of RAM, and either an Nvidia GTX 1070 8GB or AMD RX Vega 56 8GB graphics card.
Unfortunately, Bethesda did not give out any more details, so we'll have to wait for it to launch and check out how it behaves on different resolutions. There will be plenty of graphics details to turn on or off, and it will have native support for ultra-wide monitors.
You can check out more over at Bethesda's RAGE 2 website.